Anyone taking Danazol?

[txnmomma]

My dad was rx’ed Danazol. He used to take Thalidomide, but the side effects were JUST to much for him.

His dr prescribed him the Danazol recently and wanted him to try it, to see if it works for him.

Wondered if anyone else has taken it or has info about it…He has had 1 blood tranfusion and 1 plasma transfusion.

Still new to all this

[shirlsgirl]

Hi Wendy,

My mom hasn’t taken Danazol but I found an interesting article on: Prolonged complete remission of myelodysplastic syndrome treated with danazol, retinoic acid and low-dose prednisone.

http://www.ncbi.nlm.nih.gov/entrez/query…5&dopt=Abstract

Jody

[txnmomma]

Jody.. WOW, I read the link from your post.

Thank you! In fact, I printed it out so that my dad could read it..

[Neil]

Hi Wendy,
There was a patient in Florida that was on Danazol in an effort to boost platelets. It helped for about a year, maybe a little less.

[txnmomma]

Neil, ahhhhhh now my head is spinning..ughh- now I am confused. I guess I should just think of it this way.. everyone is different and meds help everyone differently.

With that said, my dad’s platelets appear to be ok. If I am correct, platelets help the blood clot [prevent and stop bleeding] This person in Fl needed Danazol for the platelet boost.

Before the MDS diagnosis, he was DVT. [Blood clots] He is currently on Coumadin for the blood clotting.

I think overall.. I am just hoping Danazol will start to work for dad.

[Neil]

Hi Wendy,
did a hematologist prescribe the Coumadin?
Is there any bleeding/bruising?

[txnmomma]

Neil…

Quote:

did a hematologist prescribe the Coumadin?
Is there any bleeding/bruising?

The coumadin was presribed 16 mnths ago @ Oct ’03 by his Family dr. He had 3-4 large clots in his leg. He doesnt have any bleedin or bruising. His PT is always checked and at one point about a month ago. He has given a plasma tx b/c his pro-time was about 120-130

Then in July 04 he was dx’ed with MDS. I have always wondered if there is a relation btwn the two.

[Neil]

Hi Wendy,
Danazol and Coumadin are an interesting combination.
Danazol was originally used to reduce menstrual bleeding in women and at one time to treat endometriosis ( did not work very well). It was somewhat effective in reducing bleeding in some MDS patients, improves clotting ability. Increased platelets in some.
Coumadin is an anti coagulant. counters clotting
Interesting combination.
Try going to a search engine and type in Danazol and then Coumadin. Take a look at the comments.

[txnmomma]

Ok..Neil, this combination.. is ummm, interesting like you said.

So the Danazol..improves clotting ability- meanwhile the Coumadin is an anti coagulant. counters clotting.

now I am really puzzled at his dr’s treatment. But then again, the hematol rx’ed the Danazol and the FP rx’ed the Coumadin. I know for a fact, his hematolog knows that he is on coumadin. The hematolog was the one that ordered 4 units of plasma one Sat for a super high pro-time.

[Neil]

Hi Wendy,
Do the 2 docs know what the other is prescribing?

[Author]

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