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mini transplant

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Viewing 7 posts - 1 through 7 (of 7 total)
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  • #4865
    Nanxy
    Member

    Do any of you, out there, have any information about a mini transplant. I have secondary MDS. Diagnosed in Sept. 05. Stanford has found a non related donor and has started the process toward a mini BMT. I have read a lot and would like any feed back that might be out there.

    #4866
    Neil
    Member

    Mini Transplants (or non-myeloablative transplants) use a less toxic chemo in preperation for the transplant than is used for the standard BMT.
    Some of the patients stem cells coexist with the donors for a period after transplantation. This reduces the risk of getting severe graft versus host disease.
    As a rule it is used on older patients, but has been used on younger patients who have not responded to standard treatment.
    There is a doc at the NIH (Dr Richard Childs) who also has had some success with them. You might want to contact him for confirmation of your situation

    #4867
    geebeebee
    Member

    Hi Nanxy,

    My mother had a “midi” stem-cell transplant that was considered to be in-between a mini and a full one. It did have a full (or nearly full) dose of chemo but no radiation. She, too, was dx with secondary MDS.

    Her doctors felt this midi one, although rougher to endure and with more risk, would provide a better chance to beat the disease than the mini. She is 120 days or so post-transplant, and her latest BMB showed no MDS, all normal blood numbers, and 98.5% donor cells. It has certainly been a tough road, with a couple of real scares, but we’re really happy with how it’s gone so far. She’s still pretty tired and weakened some of the time, but she seems to be doing better month-by-month.

    Here is a link to an article her doctor referred to initially:

    http://www.bloodjournal.org/cgi/content/abstract/104/6/1616

    Your doctor most likely will have the full version, if he subscribes to Blood Journal.

    Best of wishes in finding your treatment, and let me know if you need any more information from what my Mom had.

    Take care,

    Greg

    #4868
    Donna
    Member

    Hi Greg,
    I’m just wondering what your mom’s classification is?
    She is very close to my mom’s age, nothing was ever offered to her, as far as treatment.

    it’s wonderful that she’s doing well.

    Donna

    #4869
    geebeebee
    Member

    Thanks Donna,

    They never gave her an “official” classification. At one point they said RA, but it really progressed quickly from there.

    Greg

    #4870
    Nanxy
    Member

    Greg and Neil
    Thank you for the info. Every bit helps!
    Greg, that was interesting about your mother. Where did she have her midi stem-cell done?
    They certainly moved quickly to a transplant with her.
    again, thank you
    Nanxy

    #4871
    geebeebee
    Member

    Hi Nanxy,

    Mom had her transplant done at St. Luke’s in Kansas City, Missouri. We’ve been very impressed with the care she’s received there.

    Take care,

    Greg

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