My husband recently had his monthly blood work completed to monitor his MDS. His WBC was 24.6 and his Platelets are high at 545 (thrombocytosis). Has anybody else experienced this as and MDS patient. He has an appointment with his oncologist Monday and we are hoping for some answers. For the first time, his bloodwork shows presence of schistocytes and rouleaux formation. I am not sure how this is related to MDS, if at all. My inquiring mind always takes me to google to see if I can find any relationship between these findings, MDS and AML. The only relationship I could find is that there have been a few cases where thrombocytosis is present in patients with AML. In these cases patients were diagnosed with a chromosome 3 abnormality. Unfortunately, my husband just happens to have a chromosome 3 abnormality. I am praying he is not going to be one of the few rare cases.