Dear Claranne, When you have a low platelet count, the risk of bleeding may become evident as nosebleeds, gum bleeding, blood in the urine, or tiny purple spots under the skin. When beginning Vidaza treatment it is expected that your counts may get worse before they get better. This happens because the hypomethylating agent is deleting those cells that are not doing their job, however, in the very beginning some of the good cells get caught up in the deletion process. This is an indicator that the drug is actually working. Typically it takes between 4-6 cycles to see an increase in your counts. It also takes time for the Procrit to kick in. Hopefully your nosebleeds will subside once the medicine kicks in giving a boost to your bone marrow.