My husband had several episodes of low platelets. Typically nothing is done about it until they get to 10 or below at which time a platelet transfusion is done. The transfusion itself takes about an hour or so. If a transfusion is considered, make sure to talk to the doctor about pre-medication, i.e. benedryl and steroid to lessen any adverse / allergic reactions. I have never heard of promatca, but did read this when looking it up: “Taking Promacta may increase your risk of developing blood cancers, especially if you have myelodysplastic syndrome (also called “preleukemia”). Talk with your doctor if you have concerns about this risk.” Hopefully your doctor is well-versed in treating MDS.