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chimeric stem cell transplant

Tagged: chimeric stem cell transplant

This topic has 2 replies, 3 voices, and was last updated 4 years, 3 months ago by Dr. Lin.

Viewing 3 posts - 1 through 3 (of 3 total)

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January 2, 2020 at 12:53 pm #49913

Len Tillem
Participant

I am 75 years old.
I have been receiving Decidabin, 3 infusions every 6 weeks, so far 15 treatments.
I have received over 55 blood transfusions.
My neutrophil ANC has remained at .02 for over a year.
Fortunately I have not had any serious hospitalizations for infections.
I have very few, if any, blasts.
Recently I learned about successful chimeric stem cell transplants for MDS.
Does anyone know more about this treatment?
I am a patient at UCSF.

January 2, 2020 at 1:54 pm #49914

Sherry Pratt
Participant

Len,
I had an allogenic stem cell transplant 3 Jan 2017. I am now what they call a Chimera. My body contains 2 sets of DNA. Mine that is leftover in my saliva, nails, teeth and my donor’s (my sisters) which is the majority of my DNA now. I have not heard of the term Chimeric stem cell transplant, but this is what I know about becoming a Chimera after transplant. Hope this helps. If you need further explanation, you can email me at pratt8075@aol.com

January 8, 2020 at 8:32 pm #49932

Dr. Lin
Participant

Curative allogeneic stem cell transplant for MDS at this age is possible but not for everyone. Careful selection of the appropriate patient is the key. See this blog I wrote a couple of years back.
https://www.cancer.net/blog/2018-08/bone-marrow-transplants-and-older-adults-3-important-questions
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