Hi Greg,
At the start of the first Vidaza cycle on 10/4/2004, HCT was 37, WBC was 11.9 and Platelets were 38. At the end of the first cycle on 10/13, HCT was 36.9, WBC was 24.6 and Platelets were 35. During the first year of Vidaza treatment, there was not a lot of change in the CBC from the beginning of the Vidaza cycle and the end of the cycle. On 9/19/2005, HCT was 34.5, WBC was 10.2 and Platelets were 20. I began the 13th cycle of Vidaza on 9/19. On 10/10/2005, HCT was 35.9, WBC was 10.5 and Platelets were 16. By 10/28/2005, counts were HCT was 33.5, WBC was 12.2 and Platelets were 36 and I started cycle 14 (2 week delay in starting because of low platelets).
HCT has slowly drifted downward and is currently (4/21/2006) 25.4 (WBC is 23.2, Platelets 11). I started Aranesp on 1/9/2006 but it doesn’t appear to be helping. Platelets remain low (9-19 range). I began my 18th cycle of Vidaza on 4/24 and will finish up tomorrow. Cycles are now every 6 weeks instead of every 4 weeks in an attempt to give the counts more time to recover. CBC on Friday. I have tolerated the Vidaza well and the low counts have not yet caused any symptoms or problems.
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