Jerry, I have had low platelets for 15 years, ITP DGS until CMML DGS 2 years ago.
1)I line my right nostril with Vaseine every night (no exceptions). My septum is not straight, so left nostril nosebleeds are rare. 2) My hematologist has taken all anti-inflammatories and also Pletal (a MED for reduced blood flow to legs) out of my regime. 3) The backs of my wrists would get torn and bleed with modest bumps or abrasions. I use moisturizing lotion on my wrists; the softer skin seems more abrasion tolerant. I have not yet tried Urgent QR or Nosebleed QR, but I tend to travel with Kleenex or paper napkins to stop the bleeding when it occurs.
At any rate, I have been bleeding far less with platelets 50-60 than 2 years ago with platelets 80. Ibuprofen was quoted to me as reducing platelet effect by above 10 for a week.
No other MEDs; minimal symptons to date.