Thalidomide after Revlimid

[Leonard]

I was on Revlimid 08/06 to 04/07 5mg day. For 6 months my HGB was steady around 10. It started to drop and I’m back of TXs. Rather than increase the Revlimid dose for fear of side effects since my last white count was a little low (3.2) and I had some breathing problems he has prescribed Thalidomide 50mg 2xday. He has another MDS patient who’s been TX free on Thalidomide for 2 yrs. Anyone else switch from Revlimid to Thalidomide and what was your expericence?

[sgoodman]

I have not had expereience switching from Revlimid to Thalidomide. I switched from Thalidomide (300 mg)to Revlimid (10 mg) and would caution that I found the Thalidomide side effects to be significantly worse than Revlimid side effects at the dosage necessary to produce effects. You may want to talk to the DR about trying to move up to Revlimid 10 mg to see if that works.

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