My Mom is 89 yrs old & was diagnosed with MDS nearly a year ago. She refused to have a bone marrow biopsy due to her age and was not a candidate for treatment with the exception of transfusions due to age & other comorbidities. Her peripheral blood counts include anemia, neutropenia & thrombocytopenia plus blasts showing up in pathology report. She had a blood transfusion which was ineffective and is now Palliative. She is in pain, especially legs & arms and has shortness of breath & chest pain especially with exertion. I am so distressed at watching her go through this and am wondering about prognosis at this point. She is old, has poor mobility & her life has zero quality. Interestingly, she had tongue cancer a year and a half ago despite being a lifelong non smoker, non drinker. Surgery removed the cancer on her tongue. Lymph nodes were removed but were clear. My understanding is that her tongue cancer is unrelated to MDS. Can anyone educate me on prognosis?